Probenecid is a remedy to prevent gout attacks because it helps to eliminate excess uric acid through the urine.
In addition, probenecid is also used in combination with other antibiotics, especially the penicillin class, to increase your body time.
Indications of Probenecid
Probenecid is indicated for the prevention of gout attacks, as it helps to normalize uric acid levels in the blood. In addition, it is indicated to increase the time of some antibiotics, mainly of the class of penicillins, in the organism.
How to use Probenecid
The method of use of Probenecida includes:
- Gout: One 250 mg tablet twice daily for 1 week. Then switch to 500 mg tablets twice daily for a maximum of 3 days;
- Associated with other antibiotics:
- Adults and children over 14 years of age or weighing more than 50 kg: one 500 mg tablet 4 times a day;
- Children 2 to 14 years old or weighing less than 50 kg: start with 25 mg per kg of body weight in divided doses every 6 hours. Then, move to 40 mg per kg of body weight in divided doses every 6 hours.
Side Effects of Probenecid
The side effects of Probenecid include lack of appetite, nausea, vomiting, erythema, generalized itching, rashes on the skin and renal colic.
Contraindications of Probenecid
Probenecid is contraindicated in breast-feeding patients with kidney stones in children less than 2 years of age to treat the acute gout crisis in patients with allergy to probenecid or in patients with changes in blood cells.
The use of Probenecid in pregnant women, in patients with decreased renal function, in patients with peptic ulcer or with porphyria should only be done under guidance and medical prescription.
