Simvastatin is a remedy indicated to lower levels of bad cholesterol and triglycerides and raise levels of good cholesterol in the blood. High cholesterol levels can cause coronary heart disease due to the formation of atherosclerosis plaques, which lead to narrowing or clogging of blood vessels and consequently chest pain or myocardial infarction.
This medicine can be purchased from pharmacies in the generic form or under the trade names Zocor, Sinvastamed, Sinvatrox, among others, upon prescription.
How to take
The starting dose of simvastatin is generally 20 or 40 mg daily, taken as a single dose at night. In some cases, the doctor may decrease or increase the dose.
What is the mechanism of action
Simvastatin reduces levels of bad cholesterol by inhibiting an enzyme in the liver, called hydroxymethylglutaryl coenzyme A reductase, by reducing cholesterol production.
Who should not use
This medicine should not be used in people who are hypersensitive to any of the ingredients in the formula and who have liver disease. In addition, it should also not be used in pregnant or breast feeding women and children.
The doctor should be informed about any medication that the person is taking, in order to avoid the occurrence of drug interactions.
Possible side effects
The most common side effects that may occur during treatment with simvastatin are digestive disorders.
In addition, although rare, weakness, headache, muscle weakness or weakness, liver problems, and allergic reactions may occur, including joint pain, fever, and shortness of breath.
